This saved me from 20 hot flashes a day (and night)! I had been experiencing hot flashes over the last 5 months, and tried multiple things and supplements with no results. This made the hot flashes go away overnight! I also got my period 10 days later (and it had been 5 months since my last cycle). I do have to say it is very potent, and to go easy on it. I went a little overboard and then had estrogen dominance symptoms (gained 5 pounds suddenly). I started with 3 drops 3 times/day for 3 days. Now I've been off of it for 2 weeks and still no hot flashes. It depends how sensitive you are to DesBio products, but I would say start with 1-2 drops/day and slowly increase if needed. Awesome stuff for menopause!