ZenBiome Cope by Microbiome Labs

The Gut-Brain Axis and the Psychobiome

The gut-brain axis, a bidirectional communication between gut microbiota and the central nervous system (CNS), may play a role in cognitive function, digestion, and mood. Studies show that 80-90% of the fibers in the vagus nerve are linked to the gut, providing a physical link through which the gut microbiota communicate with the brain. Relatedly, the term psychobiome is used to describe the interaction between a person’s collective microbiome and his mental state. A diverse and balanced microbiome can help maintain the gut-brain axis. A psychobiotic is used to describe the commensal bacteria that play a role in the gut-brain axis and support brain health.

1714: A Trail-blazing Psychobiotic

Our solution to supporting the psychobiome uses cutting-edge probiotic technology. 1714, a unique strain of Bifidobacterium longum, is an up-and-coming psychobiotic that can help support the management of occasional stress and its biochemical expression within the human body. This psychobiotic exerts its effect by supporting NF-kB signaling and cytokine production, supporting IL-10 levels, and targeting the HPA axis to support healthy cortisol levels. 1714 may support mental health, cognitive process, neurotransmitters, and overall feeling of well-being. In a 4-week human trial, 1714™reduced perceived stress, improved memory performance, reduced mental fatigue, positively supported brainwave activity, and improved ability to handle occasional stress.