Dihydroberberine SR 150mg by EndurPro

Clinical research indicates berberine supports cardiometabolic health; however, the high doses needed can cause safety and tolerance issues. Dihydroberberine helps overcome these challenges for optimal patient compliance.

• Glycemic Control. A meta-analysis of randomized controlled clinical trials indicates berberine is significantly more effective in supporting glycemic balance than placebo.
• Cholesterol & Lipid Balance. Clinical research indicates berberine is effective in supporting cholesterol and lipid balance. A 2017 consensus-based position statement of an international panel of lipid experts provides clinical recommendations for the use of berberine to support cholesterol and lipid balance, recommending dosages in the range of 500-1,500 mg/day.
• Blood Pressure. Randomized controlled trials indicate berberine has a positive effect on blood pressure, suggesting supplementation may help maintain blood pressure in the normal range.
• Tolerance. Effective doses of berberine are associated with dose-dependent side effects, most notably digestive upset, which may lead some sensitive individuals to discontinue use.
• Safety. Berberine has been reported to interact with several clinically important drugs (i.e., cisplatin, cyclosporin-A, doxorubicin, fluconazole, hydroxy-camptothecine, L-DOPA, tetrandine, warfarin, thiopental,β-lactamantibiotics) resulting in either antagonistic or synergistic effects.